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CYP450 Inhibition Assays


  • Microsomes with recombinant baculovirus containing cDNA for individual human cytochrome P450 (CYP450) enzymes
  • Major CYP450 isozymes: 1A2, 2C9, 2C19, 2D6, 3A4


CYP450 Phenotyping Assays


  • To determine the actual cytochrome P450 (CYP450) responsible for the metabolism
  • Cross-species phenotyping assay
  • Metabolite identification
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