CYP450 Inhibition Assays

• Microsomes with recombinant baculovirus containing cDNA for individual human cytochrome P450 (CYP450) enzymes
• Major CYP450 isozymes: 1A2, 2C9, 2C19, 2D6, 3A4

CYP450 Phenotyping Assays

• To determine the actual cytochrome P450 (CYP450) responsible for the metabolism
• Cross-species phenotyping assay
• Metabolite identification