ONCOLOGY

Pharmidex can provide bespoke models, data evaluation and data interpretation for novel therapeutic agents to help built confidence in target biology and subsequently providing evidence of efficacy to support progression of drug candidates towards clinical evaluation.

Areas of Expertise

Dedicated drug discovery expertise to support your oncology requirements and facilitate achievement of your project objectives.


Extensive experience in data evaluation and interpretation.

Key Features

  • Bespoke models for evaluation of the pharmacology of novel agents and ascertaining target engagement


  • Data evaluation and interpretation
  • Assessment of both the pharmacokinetics of novel agents and pharmacodynamic endpoints


  • Preliminary murine toxicology

Oncology Services

Tissue-specific, different models, species and cell lines.

INDICATION ORTHOTOPIC/ HETEROTOPIC CELL LINE HUMAN (H) OR MOUSE (M) VALIDATED WITH SOC TREATMENT
Ovarian Orthotopic Heterotopic A2780 (H) & ID8 (M) PDX A2780 & ID8
Breast Orthotopic MDA-MB-231 (H) MDA-MB-231
Glioblastoma Orthotopic Heterotopic U87MG (H) GL261 (M)
Neuroblastoma Heterotopic Kelly (H)
Gastric Heterotopic NCI-N87 (H), SNU5 (H) & JIMT-1 (H)
Colorectal Heterotopic SW48 (H) & LS513 (H) SW48
Mesothelioma Orthotopic MSTO (H), JU77 (H), H2591 (H)
Skin Heterotopic A431 (H)
Lung Heterotopic A549 (H)

Oncology Bioimaging

Bioimaging is a non-invasive process that allows in vivo imaging of biological changes in the body in response to drug treatment in progressively greater depth and detail, including receptor kinetics, molecular and cellular signaling and interactions, and the movement of molecules through membranes.

Areas of Expertise

Being mostly non-invasive, bioimaging offers precise tracking of metabolites that can be used as biomarkers for disease identification, progress and treatment response.


Bioimaging is thus a powerful tool for viewing the internal workings of the body and its diseases.


At Pharmidex we offer two systems for non-invasive in vivo imaging for mouse.

Key Features

  • Elevates sensitivity, throughput and ease of use to an entirely new level


  • Combines high-sensitivity optical molecular imaging to deliver precise anatomical localization of molecular and cellular biomarkers in vivo
  • New full precision automation simplifies complex multimodal imaging protocols for small animal imaging


  • Protects your investment with a seamless upgrade path to multispectral imaging capabilities
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