Plasma & Blood Stability Assay

• Interpreting discrepancies in blood clinical samples and from in vivo pharmacokinetic studies
• Cross-species blood stability
  

Brain & Tissue Stability Assays

• Certain molecules will be unstable in tissues; this is mainly due to enzymatic processes
• Interpreting discrepancies in clinical samples and from in vivo pharmacokinetic studies
• Brain stability assay

Urine Stability Assays

• Certain molecules will be unstable in urine; this is mainly due to enzymatic processes
• Acids, antioxidants or preservatives can be added to the urine samples. Prevents compound degradation in alkaline pH urine
• Interpreting discrepancies in clinical samples and from in vivo pharmacokinetic studies
• Cross-species urine stability assay

Gastric & Intestinal Juice Stability Assays

• For orally administered drugs, the stability in gastric and intestinal fluid is an important consideration
• Using an artificial gastric fluid and intestinal recipe