PHARMACOKINETICS

Key Services



• Bespoke protocol designs available to fit project needs with experienced scientific liaisons assigned to support
• Fully integrated in vivo/bioanalysis/PK parameter determination
• Multiple routes of dose administration available, including specialised routes (please enquire)
• Pharmacokinetic profiling in a range of pre-clinical species (single and repeat dose)
• Samples can also be shipped on behalf of sponsor
• Short lead times and rapid delivery of in vivo studies
• Surgical models available in-house, including serial bile collection in Bile Duct Catheterised (BDC) species
  

• AAALAC accredited and IACUC/OLAW approved
• Collection of multiple tissue samples for drug distribution studies 
• CSF collection in multiple pre-clinical species
• In Situ BBB permeability and efflux transporter assessment
• Metabolic cages for clearance assessment in urine/faeces
  
• PK scaling to humans / human dose prediction and efflux transporter assessment
• Specialist models for CNS including microdialysis (for more info, visit our CNS service page)